Tottenham can take a giant stride towards sealing their place in the Champions League for a fourth campaign in a row by winning the 185th north London derby against Arsenal at Wembley on Saturday.
The Gunners have won 77 of the previous meetings between the sides while Spurs have 58 victories to their name and Unai Emery’s team beat their local rivals 4-2 on home soil in December – a result that extended their unbeaten run at the time in all competitions to 19 games.
Arsenal continue to impress at home but have been very vulnerable on their travels, with their 2-1 victory at Huddersfield in early February ending a six-match winless run away from Emirates Stadium.
Spurs won the corresponding fixture last season 1-0, with Harry Kane grabbing the all-important goal and it would not be a surprise to see a similar result this weekend.
Manchester City can increase the pressure on Liverpool ahead of the Reds’ Merseyside derby against Everton on Sunday by recording a comfortable victory at Bournemouth.
Since the Cherries were promoted to the Premier League, they have lost all seven of their matches against City, scoring three goals and conceding 24, and there is little to suggest Eddie Howe’s team will end that sorry run on Saturday.
City have won four of those matches by a four-goal margin and, while it may not be quite so one-sided this time, another easy victory for Pep Guardiola’s side is anticipated.
Bournemouth have been far better at home than away this term and thrashed Chelsea 4-0 in January but that has been a rare highlight for Howe’s team since October.
They are unbeaten in their last five home matches but Guardiola’s team, despite the blip at Newcastle United, remain a class act.
Brighton’s lurch towards the relegation zone is showing no sign of coming to an end, with Tuesday’s defeat at Leicester City extending their dismal run to just one win – against Everton – and eight defeats in their last 12 top-flight matches.
There is a real danger that the Seagulls’ two-season stay in the Premier League could be coming to an end although victory against rock-bottom Huddersfield would go a long way to silencing the doom-mongers.
Brighton are far better at the Amex Stadium – winning 19 of their 27 points on their own patch this season – but they will be wary of a Terriers team that gained an impressive 1-0 victory against Wolves on Tuesday.
Although Town will surely be playing in the Championship next term, they remain a hard team to break down and Brighton had to come from behind to beat them 2-1 at the John Smith’s Stadium in early December.
A draw at half time and Brighton victory at full time can be backed at 59/20.
Injury-ravaged Manchester United should add to Southampton’s relegation worries and aid their own top-four hopes by beating Ralph Hasenhuttl’s team at Old Trafford.
Saints did enjoy a brief revival when the Austrian succeeded Mark Hughes in December and they held United to a 2-2 draw at St Mary’s earlier in the campaign, but everything points to a comfortable win for Ole Gunnar Solskjaer’s outfit.
Goals are often in short supply in Southampton’s matches at both ends of the pitch, but United are currently playing well enough to break down a defence that was all at sea in the opening stages of last weekend’s 2-0 defeat at Arsenal.
Crystal Palace have won more points away from home than at Selhurst Park this season but Roy Hodgson’s team may struggle to earn a victory at Burnley.
Goals have been scarce when these two teams have met recently, with one goal being enough for each home side to win their matches last term while the Eagles recorded a 2-0 victory against Sean Dyche’s outfit in December.
Burnley’s eight-match unbeaten run may have been brought to an end at Newcastle on Tuesday but the Clarets can make it four wins and one draw from five Turf Moor matches since the Boxing Day drubbing to Everton by edging to a narrow one-goal triumph against Palace – available at 29/10.
Wolves remain well-placed to finish seventh this season in their first campaign in the Premier League since 2011/12 despite contriving to lose twice to Huddersfield and once to Cardiff.
They should avoid the ignominy of the Bluebirds also doing the double over them when they face Neil Warnock’s men at Molineux.
Cardiff have suffered heavy back-to-back home defeats to Watford and Everton in the last week.
They came from behind to beat Wolves 2-1 in November – one of only two away games Warnock’s side have won this season – and will be hoping that Nuno Espirito Santo’s outfit will have one eye on their FA Cup quarter-final clash against Manchester United in mid-March.
The mid-table clash between West Ham and Newcastle United has all the makings of a low-scoring affair, with a draw a distinct possibility.
Rafa Benitez’s side, who have moved clear of trouble by winning four of their last six games, will be keen for revenge after being beaten 3-0 by the Hammers on Tyneside three months ago.
No top-flight team has drawn more away games than Newcastle’s six, while Benitez’s team have conceded fewer goals on their travels (16) than Manchester United and Arsenal.
West Ham are one of the most inconsistent teams in the Premier League and may have to settle for a point as they did against Liverpool and Crystal Palace recently.
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