Home advantage should count on Wednesday when Manchester United take on West Ham and Arsenal entertain Southampton in the quarter-finals of the EFL Cup.
Jose Mourinho’s side had the chances to beat the Hammers on Sunday in the Premier League and they should make up for that disappointing 1-1 draw this time.
Odds on 13/2 with ComeOn! for Manchester United to win from behind look particularly tempting.
Paul Pogba and Marouane Fellaini are both suspended after picking up their fifth bookings of the season at the weekend, but Mourinho still has a wealth of talent to choose from and it may be the time for Marcus Rashford to get back on the scoresheet. The teenager is 7/5 to score at any time against the Hammers.
Mourinho’s team are eight points above their opponents in the Premier League and have lost just once at Old Trafford this season so betting at 6/1 on a routine 2-0 win for home side should be beneficial.
Slaven Bilic will be without Diafra Sakho, who scored in the second minute on Sunday, but does have Winston Reid back from suspension. The Hammers can be backed at 15/1 to clinch a shock 1-0 victory at Old Trafford.
Meanwhile, at the Emirates Stadium, Arsenal continue their quest for trophies when they come up against Claude Puel’s Southampton side.
The Gunners have not lost a game of any kind since the opening weekend of the Premier League campaign when they were beaten 4-3 by Liverpool and they returned to winning ways on Sunday when they beat Bournemouth 3-1.
It has once again been a sticky November for Wenger’s side though and they could find it difficult to break down a Saints rearguard which has been particularly mean this season.
Wenger could be without as many as eight first-teamers for the game after Olivier Giroud and Mathieu Debuchy picked up hamstring injuries against the Cherries.
Lucas Perez returns to the squad after a five-week lay-off because of an ankle problem but Santi Cazorla, Danny Welbeck, Per Mertesacker, Chuba Akpom and Hector Bellerin remain sidelined.
Saints were without both Sofiane Boufal and Steven Davis for Sunday’s 1-0 home win over Everton but both are expected to return on Wednesday.
Dusan Tadic is not expected to feature though because of a broken nose while Jeremy Pied, Matty Targett and Alex McCarthy remain sidelined.
Goals could be at a premium in the match so a 1-0 victory for Arsenal at 7/1 could be worth a punt, while the odds on both teams scoring can be backed at 20/29. Gunners striker Lucas is 29/20 to score at any time on his return to action.