These sides have had contrasting fortunes ahead of their meeting at the Stadium of Light.
Alan Pardew’s Palace side are now riding the crest of a mini-wave after securing back-to-back league wins for the first time in 2016 courtesy of a resounding 4-1 win over Stoke.
Sunderland, meanwhile, are in the midst of their now traditional slow start to the season, with David Moyes having watched his team gain one point from 15 so far.
With Jermain Defoe doubtful for this game another Sunderland loss looks likely and Palace are fancied to win at 8/5 with ComeOn!
Defoe is Sunderland’s chief goal threat – some might say only goal threat most of the time – and without him they are going to be in big trouble.
The Black Cats’ recent flirtations with the drop have been well documented in recent years but it appears this could be the season when they run out of lives.
The loss of key defender Scott Dann will be a worry for Pardew here, as Palace looked strong at the back against Stoke last week but a reshuffle will be required now.
The worry for Moyes is that, with home advantage, his side will be expected to take the game to Palace and that could be their downfall.
Wilfried Zaha, Jason Puncheon and, in particular, Andros Townsend will thrive on the chance to play fast, counter-attacking football.
Townsend was excellent in the win over Stoke, getting his first goal of the season and earning high praise from his manager.
The ex-Newcastle man will be assured of a hot reception but he could force the jeers back on the home crowd with a goal at odds 59/20.
Palace haven’t lost in three visits to the Stadium of Light while Sunderland were much better in defeat at Tottenham than the miserable home showing against Everton that went before.
The visitors can come away with a 2-0 win here which is priced at 21/2.