Could it be that on the second weekend of the new season these two sides are already staring into a fabled ‘six-pointer’ at the Kingpower Stadium?
It certainly has that feeling to it as both sides had an opening weekend to forget.
Few have predicted that Leicester will successfully defend the title they won in such spectacular, fairytale fashion last season but, even so, Claudio Ranieri and the Foxes will not want back-to-back defeats as their starting point.
Arguably, more pressure is on Arsenal going into this game after they were torn apart by Liverpool on home soil last week.
As he enters the final year of his contract, Arsene Wenger is under increasing pressure, maybe more so than at any time in his near 20-year tenure in north London.
Questions abound over Wenger’s transfer policy and if his side team is not able to quickly rectify the defensive problems of last week, this season could develop into a long and painful goodbye for the Arsenal boss.
Wenger has confirmed that Euro 2016 stars Olivier Giroud, Laurent Koscielny and Mesut Ozil are back in the fold after sitting out the defeat to Liverpool.
Arsenal are unbeaten in 12 games against Leicester and completed a home and away double against the eventual champions last season.
Wenger’s team are 29/20 to achieve another success here but, given the tameness of their defensive effort last week, that outcome requires a leap of faith.
Arsenal scored five in the corresponding fixture last season and goals look likely once more in this Saturday evening tussle.
Despite home advantage, Leicester will relish the chance to counter attack and they will take encouragement from the damage inflicted by Liverpool last Sunday against Arsenal.
Over 3.5 goals is priced at 7/4 and these sides appear set to engage in a ding-dong battle.
Neither side will be eager to countenance defeat but another reverse would surely be more damaging for Arsenal at this point.
Patience with the Gunners faithful appears to be at an all-time low for Wenger and he needs some respite ahead of what could be a vital week away from the field of play as the transfer window ticks towards closure.
A score draw would come as no surprise in this clash and therefore the chances of an even number of goals being scored at 20/23 is not without merit for what looks a devilishly tough game to predict at the home of the Premier League champions.